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How do the quantitative ER and PR Scores compare with measurements from my local pathology lab by IHC?

April 26, 2017compare er ihc lab local measurements pathology PR quantitative scores

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How do the quantitative ER and PR Scores compare with measurements from my local pathology lab by IHC?

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ER and PR by IHC measure protein expression by staining receptors on the cell surface. Quantitative ER and PR by RT-PCR measure the RNA expression of these genes. Several studies have demonstrated high concordance between ER and PR by IHC and quantitative ER and PR by RT-PCR. -+ ER and PR Scores constitute a precise, reproducible and alternate method to determine a patient’s ER and PR status.