How do the newer antidepressants compare in children?
Fluoxetine improves the symptoms of major depressive disorder in children, and the benefits of treatment may outweigh the risks, which include an increased risk of suicidal thoughts. The following antidepressants fail to improve health outcomes compared to placebo and increase the risk of suicidal thoughts and behavior: citalopram, escitalopram, sertraline, paroxetine, and venlafaxine.