How do the metrics of the DigiGait system compare to the BBB score?
The DigiGait system objectively reports over 30 metrics of posture and locomotion at a range of walking speeds. There are likely some functional measures of the Basso-Beattie-Bresnahan (BBB) score that relate to the DigiGait system’s quantitative metrics. However, most gait metrics are very sensitive to walking speeds, and walking speeds usually differ between animals in the open field. Stride lengths, for example, of a group of mice with cerebral infarction, may be significantly different at walking speeds of 20 cm/s vs. 25 cm/s, a velocity difference imperceptible to the eye. The DigiGait system also reports phase dispersion values that quantify interlimb coordination, differences in which are relevant when animals are studied at comparable walking speeds.
