How do StarDrop models compare to other models?
In independent tests, the StarDrop models have matched or exceeded the performance of other commercially available or published models. The results for the StarDrop models are shown in the tables below. If comparing the StarDrop models with other in silico models, it is important to note that the reported validation results here are for independent test sets (see “How do you validate your models?” above). It is also important, when comparing StarDrop predictions with experimental data, to ensure that this is a like-for-like comparison. For example, HIA predictions cannot be compared directly with oral bioavailability data on which both absorption and first-pass clearance will have an impact. Similarly, the StarDrop predictions for aqueous solubility are unlikely to correlate well with data obtained in a high-throughput kinetic assay based on dilution of DMSO compound stocks and will not predict the solubilities of different salt forms.
