How Do Pluripotent Cells Enable Drug Discovery?
How Do Pluripotent Cells Enable Drug Discovery? OverviewMeeting Report ▼ IntroductionEmbryonic Stem Cells and iPS CellsNew Methods and ApplicationsOpen Questions MediaResourcesSpeakers Speakers: John Hambor (Cell Therapy Group), Matthias Stadtfeld (Massachusetts General Hospital), Sheng Ding (Scripps Research Institute), and Timothy Kamp (University of Wisconsin) Organizers: Huiping Jiang and Katalin Kauser (Boehringer Ingelheim Pharmaceuticals)Presented by the Biochemical Pharmacology Discussion GroupReported by Catherine Zandonella | Posted May 13, 2010 Overview Today most drug discovery efforts involve experiments at the receptor or pathway level. Yet many drugs that are promising in vitro fail to prove safe and efficacious in vivo. Conducting drug discovery experiments in stem cells could allow researchers to understand how drug candidates interact with the entire cell rather than only with individual components. To discuss how stem cells can be used for drug discovery and developm
