How do NSAIDs cause stomach problems?
Problems caused by NSAIDs can range from mild stomach upset to stomach bleeding and ulcers. These problems occur because NSAIDs stop a substance in the body that protects the lining of your stomach from damage. At the same time, NSAIDs prevent the body’s normal ability to stop bleeding. Some people may be at higher risk for stomach problems. For example, older people are at increased risk because the normal protective substances in the stomach decline with age, making the stomach more vulnerable to the effects of NSAIDs.