How do I come off prednisolone/cortisol?
A. There should be a programmed withdrawal after a trial period of at least of 4 – 6 weeks before an attempt is made to come off the prednisolone or other adrenal support. If a downturn is experienced , you merely restart the adrenal support. If there is no downturn, the adrenals are better able to cope and adrenal support should not therefore be needed any more. Your doctor will suggest a dosage reduction plan. In general for hydrocortisone the dose may be reduced by 5 mg every 10 days, until satisfactory response is established. Prednisolone may be reduced by 2.5 mg every 14 days, until response is established.