How do I biotinylate my oligonucleotides?
9There are different ways to perform the biotinylation: – covalent linkage using aminomodified oligonucleotides and Carboxyl-Adembeads. – biotinylated oligonucleotides are also commercially available from a number of companies. We recommend to use oligonucleotides with specific biotinylation in the 5’-end to maintain the 3’-end free for elongation.
