How do genes in genetic diseases become triggered?
What is a genetic disease? A genetic disease or disorder is any disease that is caused by an abnormality in an individual’s genome. The abnormality can range from minuscule to major — from a discrete mutation in a single base in the DNA of a single gene to a gross chromosome abnormality involving the addition or subtraction of an entire chromosome or set of chromosomes. What are the different types of inheritance? There are a number of different types of genetic inheritance, including the following four modes: 1. Single gene inheritance — Also called Mendelian or monogenic inheritance. This type of inheritance is caused by changes or mutations that occur in the DNA sequence of a single gene. There are more than 6,000 known single-gene disorders, which occur in about 1 out of every 200 births. Some examples of single gene inheritance are cystic fibrosis, sickle cell anemia, Marfan syndrome, Huntington’s disease, and hemochromatosis. Single-gene disorders are inherited in recognizable
