How do drugs of abuse affect host-pathogen interactions at mucosal surfaces?
Who: David R. Brown Amount: $399,750 The mucosal epithelial cells lining the intestinal tract, lungs and other organs perform an important role in defending the body against infectious diseases such as HIV and Salmonella. Veterinary biomedical researcher David R. Brown with this funding continues his long-term studies of how opioids and other drugs of abuse reduce the ability of epithelial cells to respond to infections. Specifically, he and his team will examine how opioid drugs, such as morphine, which often are a co-factor in HIV infection, influence mucosal immune responses.
