How did the disease escape the prostate?
Just as this issue of lymph node positivity has significant implications for the management of individual patients, so does the question of whether a patient has T3 or T4 disease. In other words, if a patient is seminal vesicle positive, but otherwise the disease is localized to the prostate capsule, different treatment options may be appropriate than if the patient has clear signs that the cancer has escaped through the wall of the prostate and infiltrated the surrounding pelvic tissues.
