How did Tenchis mother Kiyone die?
That is not currently known for sure. Episode 20 does indicate that she died of old age, but considering the script Nobuyuki and Yosho used to tell Tenchi the information (written by Kiyone) and the general bizarre way her death was treated, it is hard to know for sure if in fact this is true, or just another way for K-sensei to tweak the fans.