How Did My Child Get Osteogenesis Imperfecta?
When parents who have no osteogenesis imperfecta symptoms have a child with OI, they will inquire about how this occurred in their family and about the risk of recurrence. For the great majority of these families (about 90 percent), their child’s OI was caused by a new mutation that took place in the egg or sperm near the time of conception. Their risk of recurrence in subsequent pregnancies is approximately equal to the risk of osteogenesis imperfecta in the general population.
