How common is hypoglycemia in type 1 diabetes mellitus ?
It has been stated that an individual with type 1 diabetes mellitus, who is treated for 30 years with two daily doses of insulin to avoid symptoms of hyperglycemia will have 1482 hypoglycemic episodes which are self treated, and another six severe episodes of hypoglycemia which require intravenous glucose or leading to come (Santiago RV, 1994). When the aim is to achieve euglycemia, the risk of developing hypoglycemia is much more. In the Diabetes Control and Complications Trial (DCCT) the group in intensive insulin therapy ran three times the risk of hypoglycemia compared to the conventional treatment group (DCCT, NEJM 1993….). Considering that type 1 diabetes is less commonly reported in most reports from India (ref….) what is the risk of hypoglycemia in treatment of type 2 diabetes ? The UK Prospective Diabetes Study, done in type 2 diabetes patients, is comparable to DCCT in type 2 diabetes. Mild hypoglycemia was reported in 35% of insulin treated patients after three years. In