How common are skin nodules with APO-go treatment?
Nodule formation occurs in > 1/10 of APO-go patients. Although apomorphine is rapidly absorbed from subcutaneous tissue, in some instances when the muscle underneath isn’t active enough, it can pool in the skin causing nodules to form. Nodule formation is usually not a significant problem, but occasionally, if severe, can lead to erratic absorption of the drug and may compromise the therapeutic effects. Any nodule formation can be improved with strict rotation of the injection site used and improved skin hygiene.
