How common are extraintestinal manifestations of ulcerative colitis?
The minor extraintestinal manifestations of ulcerative colitis, such as canker sores, joint pain, and tender lumps on the legs, are common and tend to accompany flare-ups. Arthritis complications occur in about 25% of patients. Dermatological changes are commonly associated with this disease. Ocular manifestations occur in 5% of patients with extensive disease. In most situations, extraintestinal manifestations respond to medical therapy.