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How common are extraintestinal manifestations of ulcerative colitis?

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How common are extraintestinal manifestations of ulcerative colitis?

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The minor extraintestinal manifestations of ulcerative colitis, such as canker sores, joint pain, and tender lumps on the legs, are common and tend to accompany flare-ups. Arthritis complications occur in about 25% of patients. Dermatological changes are commonly associated with this disease. Ocular manifestations occur in 5% of patients with extensive disease. In most situations, extraintestinal manifestations respond to medical therapy.

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