How close can I place drill holes to board edge?
You can place the holes wherever you want, but the drill hole should not overlap with the border, i.e. we can’t cut through holes. Also something very important is that if the drill hole is closer than PCB laminate thickness there is great chance during the de-panelization this thin wall between the drill hole and border to get broken, click HERE to see example of customer who placed 3.2 mm drill hole at 1.9 mm from board edge (making 0.3 mm gap between drill hole and border on 1.5 mm laminate thickness). Note that this is not DRC violation i.e. you can desing your board this way, just if you require de-panelization your holes will be broken.