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How can you make sure the tissue array cores are pathologically represented the original tissue block?

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How can you make sure the tissue array cores are pathologically represented the original tissue block?

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Tissue arrays from US Biomax usually consist of cores from 1.0 to 1.5 mm in diameter, which is an area 2.7 to 6.3 times larger than that of a 0.6 mm core tissue microarray. Thus, 1.0 mm and above core size is sufficient to represent the whole tissue section. Our high-density tissue arrays use high numbers of single cores to maximize the numbers of tissue to benefit the end users. Every 10th section of the tissue array is stained with H&E and reviewed by two board certified pathologists to make sure the pathology diagnosis is current and matched to the adjacent serial sections.

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