How can you determine if vaccine has been out of the safe temperature range long enough to affect its efficacy? Is there a set amount of time that is a guideline for vaccine thresholds?
It depends on the vaccine, the length of time it was outside of recommended storage conditions, and the environment it was in (temperature and light). The National Center for Immunization and Respiratory Diseases (NCIRD), Centers for Disease Control and Prevention recommends that whenever there is any doubt about the integrity of a vaccine it should be clearly marked “Do Not Use” and stored under appropriate conditions in a properly functioning vaccine storage unit until the integrity of the vaccine is determined. . If you have concerns about vaccine that may not have been stored or handled properly, follow your state health department immunization program policy and contact either the manufacturer’s quality control office or the immunization program for guidance. Do not assume that vaccine inappropriately exposed to light or to excessive temperatures cannot be salvaged.
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