How can we give Temodar (temozolomide) per G-tube?
Temodar capsules are indicated for the treatment of refractory anaplastic astrocytoma. The product information sheet by Schering states that the capsules should not be opened because of the carcinogenicity. Also, there is no data available on the pharmacokinetics of Temodar in any food or liquid. However, the data on file at Schering are suggestive of stability up to 120 minutes when mixed with apple juice or applesauce. Therefore, the G-tube doses may be prepared by mixing the contents of Temodar capsules with apple juice in chemo hood on daily on-call basis. Investigational Drug Services Updates: The following studies have been closed: The following studies are active: DCVax Prostate Cancer Study Apollo Study AT3 ECMO Study Baxter r-AHF-PFM Study CancerVax Melanoma Study Cardiology Fenoldopam Study Covance (diabetic foot) Study DTI 0009 Study Exclaim Study Fusion I (natrecor) Study ISO Study (UICOMP opoid study) Synergy Study Dr.