How can ulcers lead to amputation?
All diabetics are at some risk for foot ulcers because all diabetics suffer from hyperglycemia. Hyperglycemia can vary from one diabetic person to another, depending on how well they control their disease. Sustained or recurrent hyperglycemia can cause damage to the microcirculation leading to nerve damage and insensitivity and thereby lead to ulceration. Left unchecked, skin breakdown can lead to gangrene and severe damage of the tissue to a level that the body cannot heal unless the damaged part of the body is removed via an amputation.
