How can this endocannabinoid system be useful in functional gastrointestinal disorders?
The endocannabinoid system is crucially involved in the regulation of numerous gastrointestinal functions including gastrointestinal motility, sensation, secretion, inflammation, and defense under both normal and abnormal conditions. Though we presently do not know all the details about this involvement of the endocannabinoid system and on the exact mechanisms that control the correct functioning of the endocannabinoid system, we do know that we can specifically target the endocannabinoid system with drugs and thereby alter bowel function. This knowledge may be translated into future treatments where gastrointestinal inflammation is involved.
