How Can Thermo Fisher Deliver siRNAInto Cells In Vitro Without Transfection?
NAME: Devin Leake POSITION: Director, biology research and development, Thermo Fisher Scientific BACKGROUND: Senior scientist, Fisher Scientific — 2005-2006 Research scientist, Dharmacon — 2002-2005 Project manager/senior scientist, Atugen USA — 2001-2002 Postdoc, University of Colorado, Denver — 1999-2001 PhD, molecular biology/biochemistry, State University of New York, Stony Brook — 1999 BA, biochemistry, University of Texas at Austin — 1993 Last week, Thermo Fisher Scientific unveiled its Accell line of siRNAs, which it claims can be absorbed directly into cells in vitro without the need for delivery reagents, viruses, or electroporation. The company also said that the Accell siRNAs, developed by its Dharmacon unit, can penetrate every cell type that has been tested to date. This week, RNAi News spoke with Devin Leake, director of biology research and development at Thermo Fisher Scientific, about the new line of siRNAs. Let’s start with an overview of the Accell siRNAs. The Accell