How can the models built by kNN-MFA QSAR be interpreted?
The green spheres show location where steric contribution has played important role and blue spheres are the locations where electrostatic contribution has played important role. Variation in bulk in these regions would help in improving the activity. The first value in the parenthesis indicates lower limit and the second value is the upper limit of steric/ electrostatic function values for molecules. The molecule adhering to these ranges at respective field locations are likely to be in the higher activity range.
