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How can so many different organs be affected by tuberous sclerosis complex?

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How can so many different organs be affected by tuberous sclerosis complex?

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Both the TSC1 and TSC2 genes are believed to suppress tumor growth in the body. When either of these genes is defective, tumors are not suppressed and tuberous sclerosis complex results. The genes also play a role in the early fetal development of the brain and skin.

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