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How can potential nodule formation be reduced?

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How can potential nodule formation be reduced?

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Injection site should be changed daily and kept clean and hygienic. Suitable sites are the outer thighs and tummy (below the belly button). Massaging the skin either manually or using massage equipment, for between three to five minutes before insertion and after removal of the needle. Some patients find ultrasound useful, although the mechanism of action is not fully understood and evidence is anecdotal.

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