How can pcr based test be used for prenatal diagnosis of sickle cell amonia?
Diagnosis: Doctors recognize anemia, stomach and bone pain, and nausea in a young black person as signs of a sickle cell crisis. When doctors suspect sickle cell disease, they do blood tests. Sickle-shaped red blood cells and fragments of destroyed red blood cells can be seen in a blood sample examined under a microscope. Another blood test called hemoglobin electrophoresis is also done. In electrophoresis, an electrical current is used to separate the different types of hemoglobin and thus detect abnormal hemoglobin. Screening: Blood tests are done on relatives of people with the disorder because they also may have sickle cell disease or trait. Discovering the trait in people may be important for family planning, to determine their risk of having a child with sickle cell disease. Newborns are routinely screened with a blood test. Newer tests can be done during early pregnancy to screen the fetus and allow prenatal counseling for couples who are at risk of having a child with sickle ce
