How can I find out if my rDNA project is exempt from IBC review?
First, review Section III-F and Appendix C of the NIH Guidelines for Research Involving Recombinant DNA to determine the types of projects that may be exempted under the Guidelines (PI familiarity with the NIH Guidelines is a NIH requirement). NIH has exempted certain types of rDNA work from IBC approval such as simple cloning into E. coli K-12 and its derivatives, but these exemptions are very narrow and are not uniform across all types of research. The IBC and its delegates in the Biological Safety Office at EH&S have the sole authority to determine whether a specific project is exempt from review under the Guidelines. If you are planning rDNA work that you believe is exempt, please e-mail a brief summary of the work including the hosts, vectors, genes, and DNA sources (species) to bua@ucdavis.edu for review by the Biological Safety Office and the IBC. If you are working with E. coli, please specify the strain (e.g. DH5 alpha or BL21).
Related Questions
- What happens when NRCan has committed all of its funding to projects that have Technical Project Information applications in review? Will it continue to review more applications?
- Do I need to prepare an informed consent process if my project qualifies for Administrative Review (i.e., exempt status)?
- What is the deadline for submitting a research project for review by the ESCRO Committee?
