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How can I avoid cross contamination between neighboring wells on the MTP plate?

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How can I avoid cross contamination between neighboring wells on the MTP plate?

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The black patterning is hydrophobic and creates 96 square, 7 by 7 mm wells. The combination of the hydrophobic pattering and the self-adhesive silicone superstructure prevents cross contamination between the wells. It is necessary to put the superstructure accurately on the plate patterning, and press down firmly around each individual well to create a good seal.

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