How can CU be controlled?
The principal approach is to control mast cells, by controlling either the IgE stimulation or the histamine being leaked. Granted, this treats the symptom and not the cause, but until a cause is determined, it is in your best interest to try to gain some control over the symptoms. It’s a matter of working with your doctor to find the right combination of medications for you. Because skin contains receptors for H1 and H2, treatment frequently involves taking both an H1 and H2 antihistamine.