How can a repeat of the 1976 swine flu vaccine complications (Guillain-Barré syndrome) experienced in the United States of America be avoided?
Guillain-Barré Syndrome (GBS) is an acute disorder of the nervous system. It sometimes develops following a variety of infections, including influenza. Studies suggest that seasonal influenza vaccines could sometimes be associated with an increased risk of Guillain-Barré syndrome on the order of one to two cases per million vaccinated persons. During the 1976 influenza vaccination campaign, about 10 persons per million vaccinated persons developed GBS which stopped the vaccination campaign and led to the withdrawal of the vaccine. The reason why GBS developed in association with that specific vaccine has never been firmly established. The potential for the development of a similar risk with future vaccines can never be firmly excluded. However, the influenza A (H1N1) vaccine will be manufactured according to established standards and post marketing surveillance will be conducted to monitor potential development of any serious adverse events following administration of vaccine. Safety m
