How big is the work envelope?
This is the total area that the mill can possibly cut. Perhaps a more accurate definition could be the largest possible part that could be cut. Is it big enough to accommodate the work you envision? Many small CNC machines boast Y-axis travels of 4+ inches, when in reality it is much less if a vice or stock over 2″ high is used. If you want to use clamps, t-nuts, vices, fixtures, vacuum tables, etc., make certain they fit in the work area.