How are the typhoid vaccines given?
Vi antigen vaccine is given in the dose of 0.5 ml intramuscularly either on thigh or arm. It is given as a single dose. Oral ty21a vaccine is a course of 3 capsules given orally on alternate days. The capsules should be swallowed intact & not opened or chewed. In most, the pack contains 4 capsules and such 4 capsules are given on alternate days. Liquid form of oral ty21a vaccine in sachet form is more effective than the capsule form. But sachet form is not available in India. When is the typhoid vaccine given? Typhoid fever can occur at any age. 10% of cases occur in infants< 1 year of age. The most common group to be affected is school going children and adolescents. Hence earlier the vaccine is given better it is. The Vi antigen vaccine can be given only after completing 2 years of age. Oral ty21a vaccine is in form of capsules and the capsules need to be swallowed intact. Though the vaccine is effective after 2 years of age, practically a child above 4—6 years of age can swallow cap
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