How are chimeras described?
A. Example from 1TOL: A chimera can be described as a single chain with a continuous sequence. Residue numbering proceeds throughout the entire chimera. Example from 1TOL: In this example the fusion protein comprises residues 1-86 of mature minor coat protein from gene III, including glycine-rich linker (GGGSEGGGSEGGGSEGGG), residues 295-421 of protein-TOLA, and the C-terminal tail with sequence (AAAHHHHHH). PDB file snippet from 1TOL: SEQRES 1 A 222 ALA GLU THR VAL GLU SER CYS LEU ALA LYS SER HIS THR SEQRES 2 A 222 GLU ASN SER PHE THR ASN VAL TRP LYS ASP ASP LYS THR SEQRES 3 A 222 LEU ASP ARG TYR ALA ASN TYR GLU GLY CYS LEU TRP ASN SEQRES 4 A 222 ALA THR GLY VAL VAL VAL CYS THR GLY ASP GLU THR GLN SEQRES 5 A 222 CYS TYR GLY THR TRP VAL PRO ILE GLY LEU ALA ILE PRO SEQRES 6 A 222 GLU ASN GLU GLY GLY GLY SER GLU GLY GLY GLY SER GLU SEQRES 7 A 222 GLY GLY GLY SER GLU GLY GLY GLY ASP ASP ILE PHE GLY SEQRES 8 A 222 GLU LEU SER SER GLY LYS ASN ALA PRO LYS THR GLY GLY SEQRES 9 A 222 GLY ALA L