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How and why should sperm DNA damage be assessed?

April 26, 2017assessed damage dna sperm

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How and why should sperm DNA damage be assessed?

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The structural organization of sperm DNA is vital for the proper functioning of the sperm. It is not clear whether cancer itself or the various cancer treatment regimens are capable of inducing structural changes in the sperm DNA. High levels of sperm DNA damage are associated with higher miscarriage rates and lower pregnancy rates in assisted fertilization techniques. The level of DNA integrity can be assessed in a sperm sample using the SCSA (sperm chromatin structure assay). We recommend the SCSA for all sperm specimens intended for use in fertility treatment. More information for cancer patients is also available at FerileHope.