How amino acids residue form a 3D protein structure?
Proteins are long chains of amino acids, and each amino acid has an R-group. When amino acids form their chains, they end up with a lot of things that can hydrogen bond from their main chain. This makes 3D structures called alpha helices and beta sheets or beta barrels. Also, the R group gives each amino acid its properties, such as if it likes to be in water (hydrophilic) or if it doesn’t (hydrophobic). Some are acidic or basic, causing them to get + or – charges. There are some other ways that these things interact. Basically, there are several ways that proteins form their 3D structures. Hydrogen bonding, interactions with water, +s and -s attracting each other (ion pairing), some R groups will chemically bond with each other (disulfide bridges) not to mention sometimes you get multiple chains coming together to form even larger proteins.
