Have you ever used other local delivery antimicrobial agents (LDAs) like Arestin, Atridox, or PerioChip?
Atridox is the only other LDA, other than chlorhexidine gluconate or CHX, available in Canada. I have had limited use with Atridox in the past, and it was utilized only locally in unresponsive sites, after initial therapy or after the re-evaluation or at later times in recurrent periodontal disease sites. The difficulties with Atridox were primarily in the delivery system, as it was sticky and difficult to deliver to the base of the pocket. Our results were mixed, as with many LDAs, with some sites responding favorably and others not so, which may be due to many factors such as delivery, access, and the shape and size of the periodontal defect. I have never been concerned about additional costs for any treatment, as our treatment is recommended based on clinical/radiographic findings, science, and practicality for each individual patient with his/her best interest at the center of all treatment decisions.
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