Have any preclinical (laboratory or animal) studies been conducted using Newcastle disease virus?
A number of preclinical studies have been done with NDV. Research in a laboratory or using animals is done to find out if a drug, procedure, or treatment is likely to be useful in humans. These preclinical studies are done before any testing in humans is begun. The following has been learned from preclinical studies: NDV replicates more quickly in human cancer cells than in any other type of cell.Some types of NDV are able to directly kill certain types of cancer cells.NDV and NDV-infected cancer cells can cause the immune system to respond in different ways. A few of these studies used human cells, but most used animal cells. Based on these and other laboratory findings, clinical trials (research studies with people) using NDV were begun. Have any clinical trials (research studies with people) of NDV been conducted? Clinical trials of NDV have been done but have not proven that NDV is effective as a cancer treatment. Some of the trials reported positive results and some did not. Most
