Has working on HIV/AIDS opened new directions for research?
The finding of a new herpesvirus associated with KS has opened up a new area of research. For example, what is the distribution of this virus in Uganda, how is it spread, and what causes some people infected with the virus to develop KS while others do not? I am pursuing the hypothesis that in sub-Saharan Africa this herpesvirus is transmitted through blood transfusions. I hope to test this hypothesis, together with colleagues here at NCI and in Uganda, by studying Ugandan children with sickle cell anemia, who usually receive many transfusions. What is the situation for patients with HIV/AIDS in Uganda? Uganda has been fortunate in having reacted swiftly to the epidemic. The epidemic may be declining in response to educational messages. But the more that is known about HIV infection and its complications, the better the chance to reduce rates of HIV-related diseases. My being here at NCI is a step in the right direction—it should foster an international collaboration that will take kno
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