Has there been any toxicity associated with curcumin?
Two Phase I studies have been published. These studies suggests that curcumin is safe in human subjects even when consumed up to 12 grams per day for three months. Inspite of it, one is recommended to take low dose (500 mg/day) and gradually increase dose if needed. Look for signs of both potential toxicity and improvement by talking to your body and to your doctor. Return to Top Recommendations for Cancer: If you have cancer, please consider curcumin for yourself as following regimen: 1 g/day for week one; if no side effects then, 2 g/day for week two; if no side effects then (can be split into three separate doses).4 g/day for week three; if no side effects then (can be split into three separate doses). 8 g/day for week four; for eight weeks (can be split into three separate doses). After 8 weeks, if no improvement is noted, curcumin is less likely to do anything for you. If you do not have cancer, then one capsule (500 mg) per day is sufficient.
