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Has the FDA Capillary Electrophoresis (CE) method been optimized by USP?

capillary ce electrophoresis fda method optimized USP
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Has the FDA Capillary Electrophoresis (CE) method been optimized by USP?

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It has been improved by changing the concentration of heparin to 2mg/mL and changing the injection time to 30 seconds, from 10 seconds. These changes improve the resolution.

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