Has N-acetylcysteine been used in the past besides acetominophen poisoning?
Yes, to name a few… A) The problem of uncontrolled inflammation is seen in sepsis. Although as a monotherapy n-acetylcysteine has little clinical effect, therapeutic administration of n-acetylcysteine results in suppression of the constitutively activated neutrophils seen in these patients [53]. B) Administration of n-acetylcysteine to smokers results in suppression of markers of oxidative stress [54]. C) Oral n-acetylcysteine blocks angiogenesis and suppresses growth of Kaposi Sarcoma [55].
