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Has BioPORTER been used to deliver proteins into primary cells?

April 26, 2017bioporter cells deliver primary Proteins Used

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Has BioPORTER been used to deliver proteins into primary cells?

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Yes. We have delivered granzyme B into AML (acute myelocytic leukemia) cells. The delivery efficiency with this protein/cell type was approximately 40% as measured by Annexin V-FITC / propidium iodide apoptosis assay. Also, BioPORTER has been used to successfully deliver proteins into primary human dentritic cells for antigen presentation.