Has BeneFIX been used to successfully prevent bleeding in a surgical setting?
In clinical trials, BeneFIX was used to treat 28 patients who underwent major and minor surgical procedures. These procedures included liver transplantation, hernia repair, orthopedic surgeries, and dental extractions.1 Preoperative doses ranged from 25 to 155 IU/kg and postoperative doses from 30 to 169 IU/kg.15 Hemostasis was maintained throughout the surgical period; however, 1 patient required evacuation of a surgical wound site hematoma, and another patient who received BeneFIX after a tooth extraction required further surgical intervention due to oozing at the extraction site.
