Excluding the Black Plague in the 1300s, what pandemic killed the most people in history?
1918-1919 Flu some people believe that it killed even more people than the Black Plague. “The influenza pandemic of 1918-1919 killed more people than the Great War, known today as World War I, at somewhere between 20 and 40 million people. It has been cited as the most devastating epidemic in recorded world history. More people died of influenza in a single year than in four-years of the Black Death Bubonic Plague from 1347 to 1351.