Does treatment with AED after a first seizure improve the long-term prognosis for seizure remission?
Although treatment after a first unprovoked seizure may reduce the risk of a second seizure, it does not necessarily mean that it affects the long term outcome. Two randomized, prospective first-seizure studies which addressed this issue, found on evidence of a difference when treatment is started after the first seizure versus after a second seizure in achieving a 1 or 2 year seizure remission.
