Does treatment of primary HIV infection reduce transmission of HIV?
Innovative research designs must be developed to determine the relative public health impact of treatment for primary infection on the transmission of new HIV infections. Key methodological approaches include partner studies, long-term follow-up studies of viral shedding among individuals treated during primary infection, and epidemic modeling. Does treatment for primary HIV infection result in increased risk behaviors? There is strong reason to hypothesize that awareness of post exposure prophylaxis and treatment for primary HIV infection will result in adverse changes in risk-taking behavior at both the individual and community levels. Questions need to be asked and answered regarding the responses of individuals and communities to the availability of treatment for primary HIV infection. Will certain individuals who are receiving this treatment engage in more risk-taking behavior? Will certain communities respond by spreading the message that it is acceptable to revert back to higher