Does the use of hormonal therapy with salvage radiation therapy help?
Question: My original prostate cancer was a Gleason 4 + 4 = 8 adenocarcinoma with PSA of 9.1. I have a recurrence only in the area of my prostate according to my scans. My urologist is recommending hormones and radiation. What should I do? Answer: There are some studies with only a small number of patients that show that short-term hormonal therapy improves PSA freedom from recurrence and overall survival time. We need more studies to verify this finding. Currently one should seriously be considered for androgen deprivation therapy if they have high-risk features, such as a PSA greater than 10 nanograms per milliliter at the time of surgery, seminal vesicle involvement, or a Gleason score equal to or greater than 7.20.
