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Does the type of arthroscopic surgery modify the analgesic effect of intraarticular morphine and bupivacaine?

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Does the type of arthroscopic surgery modify the analgesic effect of intraarticular morphine and bupivacaine?

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Department of Anesthesia, Princesa de Espa_a Universitary Hospital, Ja_n, Spain. med500248@saludalia.comOBJECTIVE: To analyze the different analgesic response to intraarticular morphine and bupivacaine in different types of arthroscopic surgery. DESIGN: Prospective, randomized and double-blinded. Fifty-three consecutive patients undergoing an arthroscopic knee procedure under general anesthesia. They were studied separately in 2 groups (types of surgery): (1) “Low inflammatory surgery”: diagnostic arthroscopy, partial meniscectomy; and (2) “High inflammatory surgery”: ACL (anterior cruciate ligament) reconstruction, lateral release, patellar shaving and plicae removal. At the end of the procedure, patients were randomized to receive 25 mL of bupivacaine 0.25% with epinephrine (1/200,000), 5 mg of morphine, or saline (placebo) into the knee joint. Postoperative pain was determined through the visual analog scale (VAS). Supplemental analgesia (ketorolac) was administered via intravenous

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