Does the SQLitePlus COM DLL require any ODBC or OLEDB drivers (MDAC)?
No. The only dependency it has is any of the SQLite DLLs that ship with it, and possibly a Script Engine DLL if you are using Stored Scripts (see below regarding Stored Scripts). The COM DLL was deliberately created to NOT be an OLEDB driver for the purpose of NOT requiring MDAC to be installed, and for maximum performance (lightning speed).